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赛培新增产品文章：人VEGF，TNF-α，IL-6，hs-CRP酶联免疫试剂盒
发布时间：2022-09-16 17:11:01
血管腔内介入治疗糖尿病足的临床效果
刘光辉，张其润，邱福轩 [焦作煤业（集团）有限责任公司中央医院普通外科三区，河南 焦作，454000] DOI : 10 .19347/j . cnki .2096 -1413 .202218013 作者简 介：刘 光辉（1987— ），男，汉 族，河 南驻 马店 人，主治 医师 ，学士。研究 方向：周 围血 管疾 病。 Clinical effect of intravascular intervention in the treatment of diabetic foot
LIU Guanghui, ZHANG Qirun, QIU Fuxuan [No.3 Ward of General Surgery Department, Central Hospital, Jiaozuo Coal Industry (Group) Co., Ltd, Jiaozuo 454000, China] ABSTRACT: Objective To investigate the clinical effect of intravascular intervention in the treatment of diabetic foot. Methods A total of 70 patients with diabetic foot treated in our hospital from January 2019 to January 2020 were selected as the research objects. The patients were divided into internal medicine group and intervention group according to the treatment plan, with 35 cases in each group. The internal medicine group received routine comprehensive treatment, and the intervention group received intravascular intervention treatment. The therapeutic effects of the two groups were compared. Results The total effective rate of treatment in the intervention group was higher than that in the internal medicine group (P＜0.05). After treatment, the level of vascular endothelial growth factor (VEGF) increased, the levels of tumor necrosis factor-α （TNF-α）, interleukin-6 (IL-6) and high-sensitive C-reactive protein (hs-CRP) decreased, the vessel diameter and blood flow increased in both groups, and those in the intervention group were better than the internal medicine group (P<0.05). The complete disappearance time of limb numbness and hypothermia, complete healing time of ulcer wound and total length of hospital stay in the intervention group were shorter than those in the internal medicine group, the number of dressing changes during hospitalization was less than that in the internal medicine group, the visual analogue scale (VAS) score after treatment and recurrence rate within one year were lower than those in the internal medicine group, and the ankle brachial index (ABI) after treatment was higher than that in the internal medicine group (P<0.05). Conclusion Intravascular intervention is effective in the treatment of diabetic foot, which can reduce the levels of inflammatory factors and improve the hemodynamic indexes of dorsal foot and clinical indexes. KEYWORDS: diabetic foot; intravascular intervention; hemodynamic indexes of dorsal foot
